Cross CLAHRC Projects

The recent RAND Corporation report Future of Health: Findings from a survey of stakeholders on the future of health and healthcare in England commissioned by the NIHR identified multimorbidity as a key priority for research. 

In January 2018 NIHR CLAHRC East Midlands hosted the National NIHR CLAHRC Multimorbidity event. 
61 projects from across the CLAHRCs have been brought together in this document produced from the day. You can read an event summary here

This report was commissioned by the CLAHRC 
Directors to understand the breadth 
and scope of cross-CLAHRC working. 
Whilst all CLAHRCs have clear individual 
programmes of activity to achieve these 
aims, there is recognition by the CLAHRC 
Directors that collaboration across 
CLAHRCs will increase the impact of the
programme at a national level.

This report highlights the wide spectrum of 
collaborations between the NIHR CLAHRCs, with 
130 examples identified from the first three years 
of the programme (2014-2017). 
As we move into the final two years of the 
programme the Programme Managers have
planned to update this data quarterly, and we 
will propose regular updates for the Directors 
during the national meeting in September 2017.

This document has been produced in two formats - one is a summary version and one detailed version which contains all the produced maps and appendix. 

Itchy Sneezy Wheezy

We have undertaken collaborative work with NIHR CLAHRC North West London on the Itchy Sneezy Wheezy project - a project to improve diagnosis and treatment of allergies, aiming to help children in Sheffield stay out of hospital. 130 patients attended an outreach clinic in a deprived area of Sheffield. The evaluation highlights a reduction in A&E attendances for this group of children.

Trials within Cohorts (TwiCs)
In November 2014 NIHR CLAHRC YH and NIHR CLAHRC North Thames hosted the ‘TwiCs’ symposium, the purpose was to advance the development and application of this design. This event brought together triallists with practical experience of the ‘TwiCs’ design; providing an opportunity for them to share with others what they have learnt about the practical, ethical and statistical aspects of the design.  The ‘cohort multiple RCT’ is one approach to the design and conduct of pragmatic trials within cohorts. The theoretical paper describing the design can be found here: After the success of the November 2014 symposium, the Wellcome Trust have provided £15,000 to conduct a further symposium in Autumn 2016 focusing on the ethics of the trial design. The symposium will provide an opportunity for trials and ethical experts to share their experience of the ‘TwiCs’ design with patients, clinicians and ethics boards. The objectives of the symposium are to share good practice, deliver a forum in which to discuss and debate ethical issues, and identify future directions for conceptual and empirical research.